Caution - Investigational Drug; Limited by United States Law to Investigational use only.
Caution - Investigational Drug; Limited by United States Law to Investigational use only.
R&D - Ularitide

R&D

Ularitide

  • Ularitide is the pharmaceutical version of urodilatin 
  • Urodilatin is a 32 amino acid hormone of the natriuretic peptide family, secreted from the distale tubulus of the kidney 
  • Upon binding to the natriuretic peptide receptor A and stimulation of the particulate guanylate cyclase, ularitide regulates vascular perfusion, neurohormonal activation and renal function.  
  • Urodilatin is the kidneys response to decompensating heart failure by accommodating and preserving its renal function 
  • In acute heart failure, the administration of ularitide is believed to assure systemic organ perfusion and hence to reduce the short-and long term clinical complications.

Watch the following mode of action video to find out further information around how ularitide works:


Ularitide